How many spark plugs do I need to replace in my 2002 Benz E320?

Looking at a site it says that each cylinder requires 2 spark plugs.Im gonna buy Bosch platinum+4 or the IR Infusion spark plugs(the best I can find unless U have any suggestions)but I dont know if I only need 6 of those b/c it doesnt say that 2 spark plugs are required for those spark plugs.And should I replace the spark plug wires also when buying new spark plugs.How many spark plugs do I need to replace in my 2002 Benz E320?If you replace the plugs... replace them all. EVERYONE! with whatever brand you like... personaly I like the Bosh Platinum 4's as well. And yes replace the wires too.How many spark plugs do I need to replace in my 2002 Benz E320?it depends on the size of the motor and sometimes you don't need new wires it depends on te last time you replaced themHow many spark plugs do I need to replace in my 2002 Benz E320?6. and theres no need to change plug wires.How many spark plugs do I need to replace in my 2002 Benz E320?Standard cars usually only have 1 for each cylinder. It may be worth checking for corrosion on the leads before changing.